翻訳と辞書 Words near each other ・ Prostitution in ancient Greece ・ Prostitution in ancient Rome ・ Prostitution in Angola ・ Prostitution in Argentina ・ Prostitution in Armenia ・ Prostitution in Asia ・ Prostitution in Australia ・ Prostitution in Austria ・ Prostitution in Bahrain ・ Prostitution in Bangladesh ・ Prostitution in Belize ・ Prostacyclin receptor ・ Prostacyclin synthase ・ Prostaglandin ・ Prostaglandin analogue ・ Prostaglandin antagonist ・ Prostaglandin D2 ・ Prostaglandin D2 receptor ・ Prostaglandin D2 synthase ・ Prostaglandin DP1 receptor ・ Prostaglandin DP2 receptor ・ Prostaglandin E ・ Prostaglandin E synthase ・ Prostaglandin E1 ・ Prostaglandin E2 ・ Prostaglandin E2 receptor ・ Prostaglandin E3 ・ Prostaglandin EP1 receptor ・ Prostaglandin EP2 receptor ・ Prostaglandin EP3 receptor Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Prostaglandin antagonist ： ウィキペディア英語版 Prostaglandin antagonist A Prostaglandin antagonist is a hormone antagonist acting upon prostaglandin. NSAIDs inhibit cyclooxygenase and reduce prostaglandin synthesis. Corticosteroids inhibit phospholipase A2 production by boosting production of lipocortin, an inhibitor protein. Relatively new drugs, known as COX-2 selective inhibitors or coxibs, are used as specific inhibitors of COX-2. The development of these drugs allowed the circumvention of the negative gastrointestinal effects while effectively reducing inflammation. ==Adverse effects== Both NSAIDs and Coxibs can raise the risk of myocardial infarction, when taken on a chronic basis for at least 18 months. One emerging hypothesis that may explain the cardiovascular effects is that coxibs create an imbalance in circulating TxA2 (thromboxane) and PGI2 (prostacyclin) levels. An increased in the ratio of TxA2/PGI2 could lead to increased platelet aggregation and dysregulation of platelet homeostasis.〔Cheng Y et al., Role of prostacyclin in the cardiovascular response to thromboxane A2. “Science” 2002;296:539-51. PMID 11964481.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Prostaglandin antagonist」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.